MANCHESTER, NH -- (Marketwired) -- 09/16/14 -- Boston Therapeutics, Inc. (OTCQB: BTHE) ("Boston Therapeutics" or "the Company"), a developer of complex carbohydrate therapeutics to treat diabetes and inflammatory diseases, will present data on BTI-320, its lead drug candidate, as a poster presentation at the 50th Annual Meeting of the European Association for the Study of Diabetes (EASD 2014), to be held September 15-19 in Vienna, Austria.
The poster, titled "Insight into the molecular mechanism of action of BTI-320, a non-systemic novel drug to control serum glucose levels in individuals with diabetes," was written by a team of researchers led by Kevin H. Mayo, Ph.D., a professor in the Department of Biochemistry, Molecular Biology and Biophysics at the University of Minnesota, Minneapolis. Dr. Mayo led the pre-clinical study that recently discovered molecular mechanism of action of BTI-320. The poster's co-authors include David Platt, Ph.D., CEO of Boston Therapeutics, and Benjamin Rivnay, Ph.D., Chief Scientist.
The team investigated whether two substances in BTI-320 (galactomannans GM-a and GM-b) interact directly with hydrolyzing enzymes that break down carbohydrates like starch, sucrose or maltose into glucose, and can function to attenuate the rate of glucose release from digested foods. The researchers concluded that GM-a acts as a competitive inhibitor of maltase and sucrase, and possibly of a-amylase, and is the more active ingredient in BTI-320.
Dr. Platt said, "Our findings provide insight into how BTI-320 might function in vivo and support the potential viability of BTI-320 as an alternative to acarbose therapy for glycemic control in patients with diabetes. We are proud to be able to present this research at EASD 2014 and will continue to report additional findings as we obtain them."
BTI-320 is a non-systemic chewable complex carbohydrate-based compound designed to reduce post-meal elevation of blood glucose in Type 2 diabetic patients. BTI-320 is a proprietary polysaccharide to be taken before meals and works in the gastrointestinal tract to block the action of carbohydrate-hydrolyzing enzymes.
About Boston Therapeutics, Inc.
Boston Therapeutics, headquartered in Manchester, NH, (OTCQB: BTHE) is an innovator in designing compounds using complex carbohydrate chemistry. The company's product pipeline is focused on developing and commercializing therapeutic molecules that address diabetes and inflammatory diseases, including: BTI-320, a non-systemic therapeutic compound designed to reduce post-meal glucose elevation, and IPOXYN, an injectable anti-necrosis drug designed initially to treat lower limb ischemia associated with diabetes. The company also developed and currently markets SUGARDOWN®, a non-systemic complex carbohydrate-based dietary food supplement designed to support healthy blood glucose. More information is available at www.bostonti.com.
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Upon receipt of FDA approval, we may face competition with other drugs and treatments that are currently approved or those that are currently in development, which could have an adverse effect on our ability to achieve revenues from our approved products. Plans regarding development, approval and marketing of any of our compounds, including BTI-320, are subject to change at any time based on the changing needs of our company as determined by management and regulatory agencies. We have incurred operating losses since our inception, and our ability to successfully develop and market drugs may be affected by our ability to manage costs and finance our continuing operations. For a discussion of additional risk and other factors affecting our business, see our Annual Report on Form 10-K for the year ended December 31, 2013, and our subsequent filings with the SEC. You should not place undue reliance on forward-looking statements, and actual results may differ materially from the results anticipated in our forward-looking statements. Although subsequent events may cause our views to change, we disclaim any obligation to update forward-looking statements.
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Source: Boston Therapeutics